Dissociation energies of deoxyribose nucleotide dimer anions measured using blackbody infrared radiative dissociation

ARTICLES Blackbody Infrared Radiative Dissociation of Oligonucleotide Anions

The dissociation kinetics of a series of doubly deprotonated oligonucleotide 7-mers [d(A)7 , d(AATTAAT), d(TTAATTA), and d(CCGGCCG)] were measured using blackbody infrared radiative dissociation in a Fourier-transform mass spectrometer. The oligonucleotides dissociate first by cleavage at the glycosidic bond leading to the loss of a neutral nucleobase, followed by cleavage at the adjacent (59) ...

Electron capture induced dissociation of water embedded nucleotide anions

Bond dissociation energies

The bond dissociation energy (enthalpy) is also referred to as bond disruption energy, bond energy, bond strength, or binding energy (abbreviation: BDE, BE, or D) . It is defined as the standard enthalpy change of the following fission: R−X → R + X . The BDE, denoted by Do(R−X), is usually derived by the thermochemical equation, Do(R−X) = ∆fH o(R) + ∆fH o(X) – ∆fH o(RX) . The enthalpy of format...

Collision-induced dissociation of fluoropyridinide anions

Collision-induced dissociation of ortho-fluoro, meta-fluoro, and 2,6-difluoropyridinide anions are studied using the selected ion flow tube echnique. Structures and energetics of the reactants, transition states, and products are calculated at the MP4(SDQ)/6-31 + G(d) level of theory ased on the B3LYP/6-311++G(d,p) and/or MP2/6-31 + G(d) optimized geometries. The monofluoropyridinide anions (C5...

Electron Detachment Dissociation and Infrared Multiphoton Dissociation of Heparin Tetrasaccharides.

Heparin glycosaminoglycans (GAGs) present the most difficult glycoform for analytical characterization due to high levels of sulfation and structural heterogeneity. Recent contamination of the clinical heparin supply and subsequent fatalities has highlighted the need for sensitive methodologies of analysis. In the last decade, tandem mass spectrometry has been increasingly applied for the analy...